Study: some air pollutants increase the risk of breast cancer
The results of a study conducted on thousands of women in France showed that exposure to a number of air pollutants may lead to an increased risk of breast cancer, which is consistent with the findings of other recent research.
The study, called “xenair”(Xenair), confirmed among its conclusions that exposure to nitrogen dioxide increases the risk of breast cancer.
The study was carried out by members of the British University of Leicester, the Lyon Berard center and the Lyon Central School in the south-east of France, the Gustave Roussy Institute in the Parisian region, the National Institute of industrial ecology and hazards (Inneris) based north of Paris, and the Population Health Center in Bordeaux (south-west France).
Previous studies have already shown genetic or hormonal risk factors that cause breast cancer, which is the most common in women among the types of cancer, as well as factors related to age or lifestyle (alcohol, physical activity, etc.). In recent years, however, several studies have highlighted the role of certain pollutants.
The authors of a meta-analysis published in 2021 pointed out that exposure to nitrogen dioxide is one of these risk factors, and they considered that about 1,700 cases of breast cancer each year in France could be linked to it. They considered that the results on the risks associated with fine particles are not so certain.
some air pollutants increase the risk of breast cancer
As for the authors of the “ksenir” study, they studied the relationship between the risk of breast cancer and chronic exposure to low doses of eight air pollutants, namely pollutants with xenoestrogenic properties, such as dioxins, benzopyrene (BaP), polychlorinated biphenyls and cadmium – and pollutants to which exposure is daily, namely fine particles (PM10 and PM2.5), nitrogen dioxide(NO2), and ozone(O3), according to a statement issued by them.
The study included 5,222 breast cancer cases diagnosed between 1990 and 2011 from a national group that was followed for 22 years, compared with a similar number of healthy cases.
The average and cumulative exposures per woman for each pollutant were estimated, taking into account several data, including places of residence.
It turns out that the risk of developing breast cancer increases in cases of exposure to nitrogen dioxide. It was also found that the increased risk is associated with benzo “a” pyrene and PCB-153, which are the causative agents of endocrine disorders.